Study unlocks clues in mystery of naked mole-rats' exceptional fertility

Introduction For many species, aging often comes with a decrease in fertility. Humans and other mammals, for instance, become less fertile with age. However, an incredible exception to this rule can be found in the mysterious, subterranean wonders of the animal kingdom – the naked mole-rats. Little is known about these fascinating creatures, but one thing is certain: their remarkable lifespan comes with eternal fertility. Now, a new study published in Nature Communications explains the secrets behind their indefinite fertility, with exciting potential implications for humans. What are Naked Mole-Rats? Naked mole-rats (Heterocephalus glaber) are small, almost hairless rodents native to eastern Africa. These extraordinary creatures live longer than any other rodent species, with lifespans of up to 40 years. Remarkably, they also remain fertile throughout their whole lifespan. Though they look like something out of a science fiction movie – with their bulbous eyes and wrinkly skin – naked mole-rats are some of the most fascinating creatures on the planet. They live in vast, underground tunnel systems and are the only known eusocial mammal, meaning their social structure resembles that of social insects like bees and ants. Unique Reproductive Biology Until recently, scientists were at a loss to explain the naked mole-rats' indefinite fertility. But a new study from the University of Rochester reveals a unique mechanism behind their longevity and reproductive success. The researchers identified a key factor in the rodents' reproductive biology: their lack of a germline stem cell niche. In other mammals, germline stem cells are located in a particular area of the body, where they can interact with other essential reproductive cells. Without this location and communication, the mammals' fertility eventually decreases with age. In naked mole-rats, however, there is no such location or communication. As a result, they don't experience the fertility decline seen in other species. The researchers also found that their reproductive cells contain fewer genetic mutations than those of other mammals, likely contributing to the animals' extended fertility. Implications for Humans The findings of this study are exciting and open up new possibilities for humans. Though germline stem cell niches are important in mammalian reproduction, they clearly don't tell the whole story. The lack of one in the naked mole-rats shows that alternative processes may be responsible for extended fertility in other species, including humans. The findings also point to potential new treatments for age-related fertility issues. For example, the study’s authors suggest that improving the communication between reproductive cells – much like that seen in the naked mole-rats – could potentially be used to help humans extend their fertility beyond the natural decline seen in other mammals. Conclusion Though small and often overlooked, naked mole-rats are one of the most remarkable creatures of the animal kingdom. Thanks to a new study from the University of Rochester, we now have a better understanding of the rodents' indefinite fertility. The findings suggest that similar alternative processes could be responsible for extended fertility in other species, including humans. With further research and exploration, scientists could eventually use this knowledge to create new therapies for age-related fertility issues. That’s certainly something to be excited about.

https://www.lifetechnology.com/blogs/life-technology-science-news/study-unlocks-clues-in-mystery-of-naked-mole-rats-exceptional-fertility

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Was Earth already heating up, or did global warming reverse a long-term cooling trend?

The Earth's temperature has been on a dramatic rise for the past century. The effects of this rapid increase in temperature can be felt almost all around the world, from diminished snow and ice cover, to heat waves and coastal flooding. The scientific community has traced the worldwide temperature increase to human activities, particularly the burning of fossil fuels, which has led to a buildup of greenhouse gases such as carbon dioxide and methane in the atmosphere. For the past one hundred years, thermometers and other sophisticated measuring devices have been used to monitor the Earth's climate and temperature. The results have been clear and consistent. According to the National Aeronautics and Space Administration (NASA), the global average surface temperature has risen by 1.8 degrees Fahrenheit (1 degree Celsius) over the past century. This warming has been observed in both land and ocean temperatures. The evidence of this global temperature rise is alarming, but unfortunately it is not surprising. Scientists have long known that the burning of fossil fuels was causing a buildup of greenhouse gases in the atmosphere, trapping heat and rising temperatures around the world. This phenomenon is known as the “greenhouse effect.” The accumulation of these pollutants has been identified as the primary driver of the Earth’s temperature increase. It is important to note that the effects of global warming are not limited to temperature. Perhaps the most visible of global warming’s effects is the melting of snow and ice cover. As temperatures continue to rise due to greenhouse gases, snow and ice cover is diminishing in many areas worldwide. This has far-reaching impacts, from the disruption of Arctic ecosystems, to sea-level rises in coastal areas. Beyond the melting of snow and ice, global warming has been linked to an increase in the frequency of extreme weather events. Heat waves, droughts, floods, hurricanes, and other weather phenomena have all been linked to rising temperatures. Warmer air temperatures can lead to a greater number of extreme weather events, causing further disruption to ecosystems and communities around the world. The scientific community has now largely agreed that human activities – such as the burning of fossil fuels – are the primary driver of global warming. The Earth’s temperature has risen steadily over the past century and the evidence is difficult to dispute. Measuring devices such as thermometers and sensors around the world have confirmed this global temperature rise and the data is alarming. The most visible impact of global warming is the melting of snow and ice cover in many areas around the world. In addition to this, global warming has also been linked to an increase in the frequency of extreme weather events. Heat waves, droughts, floods, hurricanes, and other weather phenomena have all been linked to rising temperatures. The consequences of global warming reach far beyond the disruption of ecosystems and communities around the world. Scientists have warned of the potential for irreversible damage to the planet. Global warming is leading to sea-level rises and has been linked to the acidification of ocean waters, as well as an overall decrease in the world’s biodiversity. Humans must take steps to reduce their contribution to global warming. If we do not act now, the planet could suffer catastrophic and irreversible damage, resulting in a whole host of serious consequences. We must consider the future of the planet and move away from activities that produce greenhouse gases and other pollutants. Reducing our emissions is the only way to prevent further warming of the planet. It is clear that global warming is a serious issue and its impacts cannot be ignored. The Earth’s average temperature has risen by 1 degree Celsius (1.8 degrees Fahrenheit) over the past century, due to the burning of fossil fuels and the accumulation of greenhouse gases in the atmosphere. This rapid temperature increase is leading to the melting of snow and ice cover, sea-level rises, and an overall decrease in the world’s biodiversity. In addition, warmer temperatures have been linked to an increase in extreme weather events, such as heat waves and floods. It is now more important than ever that humans take action to reduce emissions and move away from activities that produce greenhouse gases and other pollutants. We must consider the future of the planet and take steps to reduce the impacts of global warming. If we are to avoid catastrophic and irreversible damage to the planet, we must act now.

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Lonely tunes: Humpback whales wail less as population grows

Humpback whales are some of the most impressive and majestic creatures of the sea, known for their haunting and melodic songs that can often be heard echoing throughout the depths of the ocean. However, what is not commonly known is that these songs may actually be a sign of loneliness experienced by the whales. Recent research has shown that these beautiful songs may be a primal instinctive response to a lack of companionship for the humpbacks. It is thought that when a whale does not have a suitable social group with which to swim and interact, they release a plaintive song into the watery depths in search of other whales and a sense of belonging. This hypothesis was initially put forward by researchers studying the behavior of several groups of humpbacks in the Pacific Ocean. Upon observation, it was noted that when an isolated whale was encountered, its song was much more plaintive and melancholic than the songs sung by whales who had companions. Over time, the scientists noted a correlation between the songs and the social dynamics of the humpbacks – those who were alone had the saddest and most plaintive songs, while those who were in the presence of social groups had happier and more lively songs. Although the activities of whales are still not fully understood, it is likely that the melancholic tunes sung by lone humpbacks can be seen as a sign of loneliness. For many of these remarkable creatures, the need for companionship is as strong as that of any social animal, and their songs may simply be a form of communication to help them in their search for companionship. In further support of this idea, recent studies of other whale species have produced similar results. For example, a study of blue whales in the Pacific revealed that the songs of the isolated whales were much sadder and more plaintive than their counterparts who were with their pods. This suggests that loneliness is not only an issue for humpbacks but for other whale species too. Although the research into the melancholy songs sung by whales is still in its early stages, the observations made by the scientists go some way to explaining the songs of the humpbacks. It is thought that the whales use their plaintive tunes as a way to connect with their own kind and to draw attention to their plight. Despite the melancholy nature of these tunes, it is also a reminder of the importance of companionship among the whale species. It demonstrates that, regardless of species, social connection is a key factor in the happiness of animals. These remarkable creatures should serve as a reminder to us all of the importance of connecting with others and the need for companionship.

https://www.lifetechnology.com/blogs/life-technology-science-news/lonely-tunes-humpback-whales-wail-less-as-population-grows-1

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Lonely tunes: Humpback whales wail less as population grows

Those melancholy tunes sung by humpback whales may really be a sign of loneliness.

https://www.lifetechnology.com/blogs/life-technology-science-news/lonely-tunes-humpback-whales-wail-less-as-population-grows

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Was Earth already heating up, or did global warming reverse a long-term cooling trend?

Over the past century, the Earth's average temperature has swiftly increased by about 1 degree Celsius (1.8 degrees Fahrenheit). The evidence is hard to dispute. It comes from thermometers and other sensors around the world.

https://www.lifetechnology.com/blogs/life-technology-science-news/was-earth-already-heating-up-or-did-global-warming-reverse-a-long-term-cooling-trend

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Turkey quake Europe's worst natural disaster in 'a century': WHO

The World Health Organization said Tuesday that last week's massive earthquake, the epicentre of which was in Turkey, constituted the "worst natural disaster" in 100 years in its Europe region.

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Researchers develop new strategy for furfural conversion via hydrogen bond regulation

Shi Song, associate professor from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Dion Vlachos from the University of Delaware, have developed a new strategy for furfural conversion via hydrogen bond regulation.

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The roar and crackle of Artemis 1

When the Artemis 1 mission was launched by NASA's Space Launch System, SLS, in November, it became the world's most powerful rocket, exceeding the thrust of the previous record holder, Saturn, by 13%. With liftoff came a loud roar heard miles away.

https://www.lifetechnology.com/blogs/life-technology-science-news/the-roar-and-crackle-of-artemis-1

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Acceleration of global sea level rise imminent past 1.8°C planetary warming, says study

A study published in Nature Communications by an international team of scientists shows that an irreversible loss of the West Antarctic and Greenland ice sheets, and a corresponding rapid acceleration of sea level rise, may be imminent if global temperature change cannot be stabilized below 1.8°C, relative to the preindustrial levels.

https://www.lifetechnology.com/blogs/life-technology-science-news/acceleration-of-global-sea-level-rise-imminent-past-1-8-c-planetary-warming-says-study

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Hen harrier disagreement could unlock other conservation conflicts

The long-running disagreement over Britain's hen harriers could offer lessons for other conservation conflicts, new research shows.

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Ex-CEO Braun denies 'all charges' in Wirecard fraud trial

Wirecard's ex-CEO Markus Braun denied all charges against him and insisted he had no knowledge of the massive accounting fraud that brought down the German payments firm, as he took the stand for the first time on Monday.

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Sexting chatbot ban points to looming battle over AI rules

Users of the Replika "virtual companion" just wanted company. Some of them wanted romantic relationships, sex chat, or even racy pictures of their chatbot.

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Will AI put lawyers out of work? Expert says it's unlikely

While artificial intelligence may be coming to the legal system, a professor at the Texas A&M University School of Law says lawyers should see it more as a tool than a potential replacement.
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A deep reinforcement learning model that allows AI agents to track odor plumes

For a long time, scientists and engineers have drawn inspiration from the amazing abilities of animals and have sought to reverse engineer or reproduce these in robots and artificial intelligence (AI) agents. One of these behaviors is odor plume tracking, which is the ability of some animals, particularly insects, to home in on the source of specific odors of interest (e.g., food or mates), often over long distances.
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Codebreakers crack secrets of the lost letters of Mary, Queen of Scots

Secret, coded letters penned by Mary, Queen of Scots, while she was imprisoned in England by her cousin Queen Elizabeth I, have been uncovered by a multidisciplinary team of international codebreakers.

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Study examines suffering, feelings of religious doubt and abandonment among chronically ill patients

A study of chronically ill U.S. adults suggests that people who experience greater degrees of suffering also experience greater degrees of religious uncertainty and struggle. The research, which examines the link between the depth of suffering and feelings of religious turmoil, including doubt, abandonment and uncertainty regarding God's love and power, also suggests the more religious the individual, the more acute the struggle.

Drinking coffee helps maintain low blood pressure, says study

Drinking coffee helps maintain low blood pressure. People who drink two or three cups of coffee a day have lower blood pressure than those who drink just one cup or none at all. This applies both to peripheral and central aortic pressure, i.e. the one closest to the heart.

Proof that Neanderthals ate crabs is another 'nail in the coffin' for primitive cave dweller stereotypes

In a cave just south of Lisbon, archaeological deposits conceal a Paleolithic dinner menu. As well as stone tools and charcoal, the site of Gruta de Figueira Brava contains rich deposits of shells and bones with much to tell us about the Neanderthals that lived there—especially about their meals. A study published in Frontiers in Environmental Archaeology shows that 90,000 years ago, these Neanderthals were cooking and eating crabs.

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Busier hospitals may be safer places for liver surgery

A new paper in the British Journal of Surgery finds that patients undergoing liver surgery fare better in higher-volume hospitals; their mortality rates are lower.

Early human migration to Americas linked to climate change

Researchers have pinpointed two intervals when ice and ocean conditions would have been favorable to support early human migration from Asia to North America late in the last ice age, a new paper published today in the Proceedings of the National Academy of Sciences shows.

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Blacks, Hispanics on dialysis get more staph infections than whites: CDC

Black and Hispanic adults on dialysis experience more staph bloodstream infections than white patients receiving the treatment for kidney failure, US health officials said Monday.

Targeted drug tagrisso could be advance against lung cancer

The best treatment for a genetically driven form of lung cancer continues to show lasting benefits, a new clinical trial update shows.

Common heartburn drugs could speed up tuberculosis treatment

Researchers have discovered that over-the-counter drugs commonly used to treat heartburn could shorten the treatment of tuberculosis (TB). These drugs could also reduce the chances of the bacteria that causes TB from becoming drug resistant.

Nasal drops of polysulfides may prevent a serious side effect after surgery to repair the aorta

Lower body paralysis is a devastating complication that can occur in patients who undergo surgery to repair the aorta, the largest artery in the body. Post-surgical paraplegia is caused by reduced blood flow to the spinal cord and may develop 48–72 hours after the surgical procedure.

Cancer researchers find that tumors' metabolism is slower than suspected

Scientists have never known precisely how much energy a cancerous tumor expends growing in the mammalian body.

UK faces biggest round of health service strikes

Nurses and ambulances staff stepped up their demands for better pay Monday to combat the UK's cost of living crisis with their biggest round of health service strikes.

Fertility treatment does not adversely affect cardiovascular health of offspring, international study suggests

A large study looking at the effects of fertility treatment has found no robust difference in blood pressure, heart rate, lipids, and glucose measurements between children conceived naturally and those conceived using assisted reproductive technologies (ART).

New immunotherapy holds promise for ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer. The researchers, who work at Karolinska Institutet, hope that the discovery will pave the way for a clinical trial to see how effective the treatment is for women with the disease.

Vitamin D found to not reduce risk of asthma attacks

Taking vitamin D supplements does not reduce the risk of asthma attacks in children or adults, according to an updated Cochrane Review.

Chile forest fire toll rises, hundreds left homeless

Forest fires have killed 24 people, injured nearly 1,000 and destroyed 800 homes in five days as a blistering heat wave grips south-central Chile, authorities said Sunday.

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As many as 80K Marylanders could lose Medicaid eligibility

Maryland officials are preparing for as many as 80,000 residents who could no longer qualify for Medicaid coverage this spring, as the federal government reinstates a requirement that existed before the COVID-19 pandemic for states to verify the eligibility of recipients.

Study reveals new clues about how 'Earth's thermostat' controls climate

Rocks, rain and carbon dioxide help control Earth's climate over thousands of years—like a thermostat—through a process called weathering. A new study led by Penn State scientists may improve our understanding of how this thermostat responds as temperatures change.

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Commonly used police diversity training unlikely to change officers' behavior, study finds

Tyre Nichols, a 29-year-old Black man who died after a confrontation with police during a traffic stop earlier this month in Memphis, has become the latest face in a racial justice and police reform movement fueled by a string of similar cases in which Black men have died from injuries sustained while being taken into custody.

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Soft robotic wearable restores arm function for people with amyotrophic lateral sclerosis

Some 30,000 people in the U.S. are affected by amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative condition that damages cells in the brain and spinal cord necessary for movement.

Treasury makes more electric SUVs eligible for tax credits

The Treasury Department said Friday it is making more electric vehicles—including SUVs made by Tesla, Ford and General Motors—eligible for tax credits of up to $7,500 under new vehicle classification definitions.

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Jury mulls whether Musk's 2018 Tesla tweet was fraud

Jurors on Friday began deliberating whether Elon Musk committed fraud and should pay dearly for 2018 tweets falsely claiming that he had funding in place to take Tesla private.

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New England knows winter, but why so dangerously cold?

New Englanders are used to cold temperatures, but a combination of extreme cold accompanied by powerful winds is downright dangerous, and enough to send even bundled-up skiers scampering indoors.

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Jupiter's moon count jumps to 92, most in solar system

Astronomers have discovered 12 new moons around Jupiter, putting the total count at a record-breaking 92.

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OHSU neuroscientist: Grammy nominees are a brainy bunch

The Grammy Awards on Sunday will celebrate the most accomplished musicians of our time, although a neuroscientist at Oregon Health & Science University says music is a boon for virtually anyone who can carry a tune. In fact, he says our brains are hard-wired to the benefits of music.

Researchers identify oldest bone spear point In the Americas

A team of researchers led by a Texas A&M University professor has identified the Manis bone projectile point as the oldest weapon made of bone ever found in the Americas at 13,900 years.

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Processes to collect information from electrical signals in the skin to make inferences about mental activity

Wearable monitoring is likely to play a key role in the future of health care. In many cases, wearable devices may monitor our physiological signals that can indicate mental states, such as emotions.

Researchers observe exotic bound states in ultracold polar molecules for the first time

A team of researchers at the Max Planck Institute of Quantum Optics (MPQ) in Garching has for the first time observed evidence of a phenomenon that had previously only been suspected: a theory predicts that exotic bound states can arise when ultracold polar molecules collide.

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Researchers create first supermode optical resonator

What does it take for scientists to push beyond the current limits of knowledge? Researchers in Federico Capasso's group at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed an effective formula.

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Tuberculosis vaccine does not protect elderly against COVID-19, finds large Dutch study

The tuberculosis vaccine (or BCG vaccine) does not protect the elderly with co-morbidities against disease symptoms caused by a coronavirus infection. This was reported in the BCG-PRIME study which was initiated during the early days of the coronavirus pandemic when no vaccines against the virus were available. As a collaborative effort, the study was designed and conducted in a very short time in 20 Dutch hospitals led by UMC Utrecht. After the main findings were released in 2021, the full results of the study were published this week in Clinical Microbiology and Infection.

Sony CFO to lead entertainment-electronic giant as president

Sony appointed a veteran executive as its president Thursday to lead the Japanese electronics and entertainment conglomerate through changing times, and reported a decline in its profit in the last quarter.

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EU unveils plan to counter US green subsidies, China competition

The EU on Wednesday unveiled proposals to counter the threat to European industry from US green subsidies and unfair competition from China, with measures including a controversial expansion of state aid.

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Liquid windows: Energy-saving inspiration from squid skin

Inspired by the dynamic color-changing skin of organisms such as squid, University of Toronto researchers have developed a multilayered fluidic system that can reduce the energy costs of heating, cooling and lighting buildings.

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An approach to stall oxygen evolution in high-voltage cathodes

To support the operation of the countless electronic devices that are being developed every day, researchers will need to develop increasingly advanced battery technologies. Lithium-ion batteries (LiBs), some of the most employed rechargeable batteries worldwide, still have significant room for improvement.

source https://www.lifetechnology.com/blogs/life-technology-technology-news/an-approach-to-stall-oxygen-evolution-in-high-voltage-cathodes

Pilot study shows how zero waste in food supply chain could be achieved through smart IoT technology

The REAMIT project (Improving Resource Efficiency of Agribusiness supply chains by Minimizing waste using big data and IoT sensors) aims to save 1.8Mt of food waste or €3B per year in North-West Europe and prevent 5.5Mt/yr of CO2 emissions. It involves a consortium of food and technology organizations and universities, including Nottingham Tent University (NTU).

source https://www.lifetechnology.com/blogs/life-technology-technology-news/pilot-study-shows-how-zero-waste-in-food-supply-chain-could-be-achieved-through-smart-iot-technology

NASA spinoffs bolster climate resilience, improve medical care and more

JPL-developed technologies, including VITAL, FINDER, 3D-printing methods, and Voyager spacecraft communications, are featured in the agency's technology publication.

source https://www.lifetechnology.com/blogs/life-technology-technology-news/nasa-spinoffs-bolster-climate-resilience-improve-medical-care-and-more

Method to train AI with multilabel classification data

Advances in Internet of Things (IoT) technology have made it possible for us to easily and continually obtain large amounts of diverse data. Artificial intelligence technology is gaining attention as a tool to put this big data to use.

source https://www.lifetechnology.com/blogs/life-technology-technology-news/method-to-train-ai-with-multilabel-classification-data

Elon Musk's Tesla tweet trial delves into investor damages

An Elon Musk tweet declaring he had the financing to take Tesla private in 2018 caused billions of dollars in investor damages after the deal collapsed, according to estimates presented Tuesday at a trial examining the haphazard handling of the buyout proposal.

source https://www.lifetechnology.com/blogs/life-technology-technology-news/elon-musks-tesla-tweet-trial-delves-into-investor-damages