It is estimated that 80% of women will suffer from vaginal candidiasis at least once in their lives. In addition to superficial infections, which can be oral or vaginal and do not usually have a serious prognosis, fungi of the Candida genus can cause systemic diseases in immunocompromised individuals and these are fatal in 40% of cases. Drugs are available to treat these conditions, but doctors are increasingly encountering varieties of fungi that have developed resistance to treatments, thus making candida infection a serious global health problem.
source https://phys.org/news/2021-10-identification-genes-resistance-treatment-pathogenic.html