When an outbreak of sylvatic plague decimated black-tailed prairie dog numbers in the Thunder Basin National Grassland in 2017, researchers saw an opportunity for a "natural experiment" to explore the impact of the rodents' die-off on the plants and other wildlife in that area of northeast Wyoming.
source https://www.lifetechnology.com/blogs/life-technology-science-news/study-details-impact-of-prairie-dog-plague-die-off-on-other-species